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Indications
Sodium chloride shortage is treated and prevented using this medication.
Pharmacology
Changes in osmotic tension influence the movement of fluids and salt diffusion in cellular tissue. Sodium chloride is the primary salt involved in maintaining the osmotic tension of blood and tissues. Where there is a sodium deficiency, a Sodium Chloride tablet supplies a source of sodium. The gastro-intestinal tract readily absorbs sodium chloride. It can be found in all bodily fluids, but particularly in extracellular fluid. The amount of sodium lost (via sweat) is usually insignificant. Surplus amounts are excreted in the urine to maintain osmotic balance.
Dosage & Administration
It is important that the tablet should be swallowed whole with water (approx. 70 ml per tablet where kidney function is normal to avoid hypernatremia), and not chewed.
Adults: For prophylaxis 8-16 tablets per day. For treatment dosage to be adjusted to individual needs up to a maximum of 40 tablets per day in case of severe salt depletion. For control of muscle cramps during routine maintenance haemodialysis usually 20-32 tablets per dialysis. In some cases of chronic renal salt-wasting, up to 40 tablets per day may be required with appropriate fluid intake.
Children: Dosage should be adjusted to individual needs.
Elderly: No special dosage adjustment.
Interaction
In hypertensive patients with chronic renal failure Sodium Chloride, 300 mg tablet may tend to impair the efficacy of antihypertensive drugs.
Contraindications
Sodium chloride is contraindicated in any circumstance where salt retention is undesirable, such as edema, heart disease, cardiac decompensation, and primary or secondary aldosteronism; or in any situation when therapy is provided to cause salt and water loss.
Side Effects
At the indicated dosage, no negative effects have been observed with Sodium Chloride 300 mg pill.
Pregnancy & Lactation
Use in Pregnancy: No additional precautions required during pregnancy.
Precautions & Warnings
No special warnings and precautions are required to maintain.
Therapeutic Class
Oral electrolytes preparations
Storage Conditions
Store below 30°C in a dry place protected from light. Keep out of reach of Children.
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